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Positive test controls include: HepG2, 293T, SW480, OVCAR3, NCI-H460, Mouse liver, Mouse brain. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein.
Immunogen sequence: KIVRGDQPAA SGDSDDDEPP PLPRLKRRDF TPAELRRFDG VQDPRILMAI NGKVFDVTKG RKFYGPEGPY GVFAGRDASR GLATFCLDKE ALKDEYDDLS DLTAAQQETL SDWESQFTFK YHHVGKLLKE GEEPTVYSDE EEPKDESARK ND
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 25-DX; Acidic 25 kDa protein; Dap1; HGNC:16090; IZA; Membrane-associated progesterone receptor component 1; membrane-bound progesterone receptor; mPR; PGRMC1; progesterone binding protein; unnamed protein product; VEMA; Ventral midline antigen
基因别名: 25-Dx; 25Dx; AA415812; Dap1; HPR6.6; IZA; Lewi; MPR; PGRMC; PGRMC1; PPMR; VEMA
UniProt ID: (Human) O00264, (Rat) P70580, (Mouse) O55022
Entrez Gene ID: (Human) 10857, (Rat) 291948, (Mouse) 53328