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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MSLQYGAEET PLAGSYGAAD SFPKDFGYGV EEEEEE
Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.
RRAGC (Ras-related GTP-binding protein C) is a monomeric guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulations of the mTORC1 signaling cascade. RRAGC forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. It cycles between an inactive GTP-bound and an active GDP-bound form. RRAGC, in its active form, participates in the re-localization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This re-localization is a crucial step in the activation of the TOR signaling cascade by amino acids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GTPase-interacting protein 2; Rag C; Ras-related GTP-binding protein C; TIB929
基因别名: RRAGC
Entrez Gene ID: (Human) 64121