Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Immunogen sequence: CPGPLAVANGV VKQLHFQEKQ MPEEPKLTLD ESYDLVVENE EVLTLQETLE ALSLSEYFST FEKEKIDMES LLMCTVDDLK EM
Highest antigen sequence identity to the following orthologs - mouse 72%, rat 73%.
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, which suggests its role in the early secretory pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: p125; SEC23-interacting protein
基因别名: MSTP053; P125; P125A; SEC23IP
UniProt ID: (Human) Q9Y6Y8
Entrez Gene ID: (Human) 11196
分子生物学功能: hydrolase lipase phospholipase metabolite interconversion enzyme