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Invitrogen
SPZ1 Polyclonal Antibody
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SPZ1 Antibody (PA5-23391) in IHC (P)
Immunohistochemistry analysis of SPZ1 in formalin-fixed, paraffin-embedded mouse testis tissue. Samples were incubated with SPZ1 polyclonal antibody (Product # PA5-23391) using a dilution of 5 µg/mL. Isotype control (top left) and this antibody (bottom left, right).
产品信息
PA5-23391
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 40-90 of human SPZ1.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The amino acid sequence used as immunogen is 82% homologous in Chicken.
靶标信息
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BHLH-Zip transcription factor SPZ1; protein phosphatase 1, regulatory subunit 148; Spermatogenic leucine zipper protein 1; Spermatogenic Zip 1; testis secretory sperm-binding protein Li 232m; Testis-specific protein 1; Testis-specific protein NYD-TSP1
基因别名: 1700027M20Rik; AI429130; NYD-TSP1; PPP1R148; SPZ1; TSP1
UniProt ID: (Human) Q9BXG8, (Mouse) Q99MY0, (Rat) Q6AXY9
Entrez Gene ID: (Human) 84654, (Mouse) 79401, (Rat) 499510
