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Antibodies Inc
TASK1 Potassium Channel Monoclonal Antibody (N374/48), FL650
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产品信息
75-357-FL650
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
N374/48
抗原
Fusion protein amino acids 251-411 (cytoplasmic C-terminus) of rat Acid-sensitive potassium channel protein TASK or TASK1 (accession number O54192) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
655/676 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acid-sensitive potassium channel protein TASK-1; Cardiac two pore background K(+) channel; cTBAK 1; cTBAK-1; KCNK9; Potassium channel subfamily K member 3; potassium channel, subfamily K, member 3; TASK 1; TWIK-related acid-sensitive K(+) channel 1; TWIK-related acid-sensitive K+ channel; Two pore K(+) channel KT3.1; Two pore potassium channel KT3.1
基因别名: Ctbak; cTBAK-1; Kcnk3; rTASK; TASK; Task-1; Task1
UniProt ID: (Rat) O54912, (Mouse) O35111
Entrez Gene ID: (Rat) 29553, (Mouse) 16527
ion channel activity
open rectifier potassium channel activity
protein binding
protein C-terminus binding
potassium ion leak channel activity
protein homodimerization activity
S100 protein binding
protein heterodimerization activity
voltage-gated ion channel activity
potassium channel activity
ion channel
transporter
brain development
ion transmembrane transport
regulation of ion transmembrane transport
response to drug
negative regulation of cytosolic calcium ion concentration
cellular response to zinc ion
cellular response to hypoxia
potassium ion transmembrane transport
cochlea development
transport
ion transport
potassium ion transport
stabilization of membrane potential
mitophagy in response to mitochondrial depolarization
