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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total TOM1L2.
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ32746; myb1-like protein 2; Target of Myb-like protein 2; TOM1-like protein 2; UNQ3124
基因别名: 2900016I08Rik; A730055F12Rik; AU042072; Srebf1; TOM1L2
UniProt ID: (Mouse) Q5SRX1
Entrez Gene ID: (Rat) 360537, (Mouse) 216810