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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ALSPIHTPQR SVPEVDPAAT MPRSQSQQRT SAGSYSSPPP APYSAPQAPA LSVTGPITAN SEQIARLRSE LDVVRGNTKV MSEML
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ32746; myb1-like protein 2; Target of Myb-like protein 2; TOM1-like protein 2; UNQ3124
基因别名: 2900016I08Rik; A730055F12Rik; AU042072; Srebf1; TOM1L2
UniProt ID: (Mouse) Q5SRX1
Entrez Gene ID: (Rat) 360537, (Mouse) 216810