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Antibodies Inc
TrpC5 Monoclonal Antibody (N67/15), FL650
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产品信息
75-104-FL650
应用
建议稀释比
已发表文章
产品规格
种属反应
Guinea pig,
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
N67/15
抗原
Synthetic peptide amino acids 827-845 of human TrpC5 (accession number Q9UL62).
偶联物
激发/发射光谱
655/676 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: SKAESSSKRS FMGPSLKKL
靶标信息
TRPC5 belongs to the transient receptor family. TRPC5 is one of the seven mammalian TRPC (transient receptor potential channel) proteins. The TRPC5 protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. TRPC5 also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). TRPC5 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, or G-protein coupled receptors. TRPC5 has also been shown to be calcium-selective, and may also be activated by intracellular calcium store depletion. Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Capacitative calcium entry channel 2; CCE2; Htrp-5; hTRP5; mtrp5; protein phosphatase 1, regulatory subunit 159; Short transient receptor potential channel 5; transient receptor potential cation channel, subfamily C, member 5; transient receptor potential channel 5; Transient receptor protein 5; TRP-5; Trp-related protein 5; TrpC5; vtransient receptor potential cation channel, subfamily C, member 5
基因别名: CCE2; PPP1R159; TRP-5; TRP5; TRPC5; Trrp5
UniProt ID: (Human) Q9UL62, (Mouse) Q9QX29
Entrez Gene ID: (Human) 7224, (Guinea pig) 100719495, (Mouse) 22067, (Rat) 140933
