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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ELNKQLKDLS QKYTEVKNVK EKLVEENAKQ TSEILAVQNL LQKQHVPLEQ VEALKKSLNG TIENLKEELK SMQRCYEKEQ QTVTKLHQLL ENQKNSSVPL A
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 77%.
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Uveal autoantigen with coiled-coil domains and ankyrin repeats
基因别名: KIAA1561; UACA
Entrez Gene ID: (Human) 55075