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Proteintech
ASIC2 Polyclonal Antibody
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产品信息
17851-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ASIC2 Fusion Protein Ag12301 (60-426 aa encoded by BC075043)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SSERVSYYF SYQHVTKVDE VVAQSLVFPA VTLCNLNGFR FSRLTTNDLY HAGELLALLD VNLQIPDPHL ADPSVLEALR QKANFKHYKP KQFSMLEFLH RVGHDLKDMM LYCKFKGQEC GHQDFTTVFT KYGKCYMFNS GEDGKPLLTT VKGGTGNGLE IMLDIQQDEY LPIWGETEET TFEAGVKVQI HSQSEPPFIQ ELGFGVAPGF QTFVATQEQR LTYLPPPWGE CRSSEMGLDF FPVYSITACR IDCETRYIVE NCNCRMVHMP GDAPFCTPEQ HKECAEPALG LLAEKDSNYC LCRTPCNLTR YNKELSMVKI PSKTSAKYLE KKFNKSEKYI SENILVLDIF FEALNYETIE QKKAYEVA (60-426 aa encoded by BC075043 )
靶标信息
ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acid sensing (proton gated) ion channel 2; acid sensing ion channel 2; acid-sensing (proton-gated) ion channel 2; Acid-sensing ion channel 2; Amiloride-sensitive brain sodium channel; Amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Amiloride-sensitive cation channel neuronal 1; ASIC2; BNC1; Brain sodium channel 1; degenerin; Mammalian degenerin homolog; MDEG; neuronal amiloride-sensitive cation channel 1
基因别名: ACCN; ACCN1; ACIC2; ASIC2; ASIC2a; BNAC1; BNaC1a; BNC1; BNC1k; hBNaC1; MDEG; MDEG1; MDEG2
UniProt ID: (Human) Q16515, (Rat) Q62962, (Mouse) Q925H0
Entrez Gene ID: (Human) 40, (Rat) 25364, (Mouse) 11418
regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
chemical synaptic transmission
central nervous system development
peripheral nervous system development
phototransduction
sensory perception of sound
response to acidic pH
regulation of gene expression
monovalent inorganic cation transport
regulation of vasoconstriction
regulation of blood coagulation
ion transmembrane transport
regulation of ion transmembrane transport
protein localization to synapse
sodium ion transmembrane transport
regulation of membrane potential
negative regulation of apoptotic process
sensory perception of sour taste
detection of mechanical stimulus involved in sensory perception
positive regulation of synapse assembly
cation transport
sodium ion transport
response to mechanical stimulus
cellular response to drug
cellular response to acidic pH
cation transmembrane transport
positive regulation of cation channel activity
transport
ion transport
