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Invitrogen
ASIC2 Polyclonal Antibody
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图: 1 / 1
ASIC2 Antibody (PA5-95378) in WB
Western blot analysis of ASIC2 in rat testis extract (lane 1) and MCF-7 whole cell lysates (lane 2). Samples were incubated with ASIC2 polyclonal antibody (Product # PA5-95378) using a 0.5 µg/mL dilution. developed was performed using enhanced chemiluminescence (ECL).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-95378
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human ACCN1 (112-147aa ELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYK).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: rat testis tissue, MCF-7 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acid sensing (proton gated) ion channel 2; Acid-sensing ion channel 2; Amiloride-sensitive brain sodium channel; Amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; Amiloride-sensitive cation channel neuronal 1; ASIC2; BNC1; brain Na+ channel-1; Brain sodium channel 1; degenerin; Mammalian degenerin homolog; MDEG; neuronal amiloride-sensitive cation channel 1; unnamed protein product
基因别名: ACCN; ACCN1; ASIC2; ASIC2a; BNaC1; BNC1; BNC1k; hBNaC1; MDEG; MDEG1; MDEG2
UniProt ID: (Rat) Q62962
Entrez Gene ID: (Human) 40, (Rat) 25364
sodium ion transport
sodium ion transmembrane transport
sensory perception of sour taste
cellular response to xenobiotic stimulus
cellular response to acidic pH
regulation of postsynapse assembly
regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
cation transport
phototransduction
sensory perception of sound
response to mechanical stimulus
response to acidic pH
regulation of gene expression
regulation of vasoconstriction
regulation of blood coagulation
ion transmembrane transport
regulation of ion transmembrane transport
protein localization to synapse
cellular response to drug
regulation of membrane potential
negative regulation of apoptotic process
detection of mechanical stimulus involved in sensory perception
positive regulation of synapse assembly
cation transmembrane transport
positive regulation of cation channel activity
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