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KLF17 Polyclonal Antibody
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KLF17 Antibody (600-401-CE8) in WB
Western Blot of Rabbit anti-KLF17 antibody. Lane A: rat liver tissue lysate in the absence of blocking peptide. Lane B: rat liver tissue lysate in the presence of blocking peptide. Primary antibody: KLF17antibody at 1 µg/mL overnight at 4°C. Secondary antibody: Goat anti-Rabbit HRP secondary antibody. Block: 5% BLOTTO. Predicted/Observed size: 28/39/43 kDa, 38 kDa for KLF17.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
600-401-CE8
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-KLF17 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human KLF17.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C2H2 type zinc finger protein; GZF; FLJ40160; germ cell specific zinc finger protein; Kruppel like factor 17; Kruppel-like factor 17; novel zinc-finger protein; unnamed protein product; zinc finger protein 393; ZLF393
基因别名: 7420700M05Rik; D4Ertd561e; Gzf; Zfp393; ZLF393; ZNF393
UniProt ID: (Human) Q5JT82, (Mouse) Q8CFA7
Entrez Gene ID: (Human) 128209, (Rat) 298449, (Mouse) 75753
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
Disclaimer
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