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Invitrogen
KLF17 Polyclonal Antibody
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产品信息
PA5-72838
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLF17 antibody for a 17 amino acid peptide near the carboxy terminus of human KLF17. The immunogen is within the last 50 amino acids of KLF17.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ40160; germ cell specific zinc finger protein; Germ cell-specific zinc finger protein; Krueppel-like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zinc finger protein 393; ZLF393
基因别名: 7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; Gzf; KLF17; Zfp393; ZNF393
UniProt ID: (Human) Q5JT82, (Mouse) Q8CFA7
Entrez Gene ID: (Human) 128209, (Mouse) 75753, (Rat) 298449
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription regulatory region DNA binding
metal ion binding
nucleic acid binding
DNA binding
C2H2 zinc finger transcription factor
