Search
Invitrogen
MTGR1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100425
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CBFA2T2(Accession O43439), corresponding to amino acid residues R259-N309.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CBFA2T2.
靶标信息
Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CBFA2/RUNX1 translocation partner 2; CBFA2T2 identified gene homolog; core-binding factor, runt domain, alpha subunit 2; core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog; core-binding factor, runt domain, alpha subunit 2; translocated to, 2; DKFZp313F2116; ETO homolog on chromosome 20; ETO homologous on chromosome 20; MTG8-like protein; MTG8-related protein 1; myeloid translocation gene-related 1; myeloid translocation gene-related protein 1; myeloid translocation-related protein 1; RP5-1137F22.1; translocated to, 2; unnamed protein product; ZMYND3 CBFA2T2
基因别名: A430091M07; C330013D05Rik; Cbfa2t2h; EHT; MTGR1; p85; ZMYND3
UniProt ID: (Human) O43439, (Mouse) O70374
Entrez Gene ID: (Human) 9139, (Rat) 296293, (Mouse) 12396
transcription, DNA-templated
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
epithelial cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
