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Invitrogen
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PA1-525 detects human SKAP55.
PA1-525 has been successfully used in Western blot, immunocytochemistry and immunoprecipitation procedures. By Western blot, this antibody detects an ~ 60 kDa protein from human Jurkat cells.This antibody has also been used in immunoprecipitation and immunocytochemical procedures.
PA1-525 antigen corresponds to amino acids 2-105 of human SKAP-55.
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。