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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DPPPHMRVPT IPPNLAGIPG GKPAYSFHVT ADGQMQPVPF PPDALIGPGI PRHARQINTL NHGEVVCAVT ISNPTRHVYT GGKGCVKVWD ISHPGNKSPV SQLDCLNRDN YIRSCKLLPD GCTLIVGGEA STLSIWDLAA PTPRIKAELT SSAPACYALA ISPDSKVCFS CCSDGNIAVW DLHNQTLVRQ FQGHTDGASC IDISNDGTKL WTGGLDNTVR SWDLREGRQL QQHDFTSQIF SLGYCPTGEW LAVGMESSNV EVLHVNKPDK YQLHLHESCV LSLKFAYCGK WFVSTGKDNL LNAWRTPYGA SIFQSKESSS VLSCDISVDD KYIVTGSGDK KATVYEVIY
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; RP11-203D19.1; TLE 1; Transducin-like enhancer protein 1
基因别名: TLE1
Entrez Gene ID: (Human) 7088