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NeoBiotechnologies
UACA/Nucling Monoclonal Antibody (UACA, 1222)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
55075-MSM2-P1
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
UACA, 1222
抗原
Recombinant human UACA protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
200 µg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: nuclear membrane binding protein; nuclear membrane binding protein NUCLING; nuclear membrane-binding protein; unnamed protein product
基因别名: 2700059D02Rik; NUCLING
UniProt ID: (Human) Q9BZF9, (Mouse) Q8CGB3
Entrez Gene ID: (Human) 55075, (Mouse) 72565
intrinsic apoptotic signaling pathway in response to DNA damage
intrinsic apoptotic signaling pathway in response to oxidative stress
negative regulation of inflammatory response
negative regulation of NIK/NF-kappaB signaling
response to UV
regulation of gene expression
positive regulation of protein import into nucleus
positive regulation of apoptotic process
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