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TMT Multiplexing Products

End-to-end solution for TMT Multiplexing quantitation

Discover the Orbitrap LC-MS-based Thermo Scientific Tandem Mass Tag (TMT) multiplexing workflow solutions, the most published in the industry for isobaric tagging applications. Delivering quantitative accuracy and precision to enable complete quantitative profiles to meet research goals.

 

The TMT multiplexing workflow offers quantification for multiplexed proteome analysis with intelligent acquisition management. Optimized workflows help ensure accurate, precise, and cost-effective identification and quantitation of thousands of proteins from multiplexed samples in a single run.

Sample preparation for TMT multiplexing

Streamline Your Sample Preparation with AccelerOme Automated Sample Preparation Platform

TMT multiplexing sample preparation can be simplified with the Thermo Scientific AccelerOme Automated Sample Preparation Platform. Enjoy faster, high-quality sample preparation with fewer touchpoints, all leading up to LC-MS analysis.

AccelerOme TMTpro MS Sample Preparation Kits

The Thermo Scientific AccelerOme TMTpro MS Sample Preparation Kits deliver efficient and reliable mass spectrometry sample preparation with TMTpro peptide labeling, optimized for use with the AccelerOme automated sample preparation platform.

TMTpro 32plex and TMTpro Deuterated Label Reagents

Thermo Scientific TMTpro label reagents represent the latest advancement in tandem mass tags, engineered to enhance sample multiplexing while maintaining high standards of protein identification and quantitation. The deuterated TMTpro label reagents allow for the multiplexing of up to 35 samples, significantly boosting throughput for protein identification and quantitative analysis mass spectrometry.

Separation solutions optimized for TMT multiplexing

Vanquish Neo UHPLC System: Perfect for experiments demanding exceptional UHPLC reproducibility and precision

Experience unparalleled performance with the Thermo Scientific Vanquish Neo UHPLC System. Designed for high-sensitivity and high-throughput TMT multiplexing experiments, it integrates seamlessly with the premier Thermo Scientific mass spectrometry portfolio and ESI sources.

EASY-Spray PepMap Neo UHPLC Columns: Perfect for experiments demanding highly reproducible separations and robust performance

Thermo Scientific EASY-Spray PepMap Neo UHPLC Columns offer deep proteome coverage with high sensitivity and retention time stability, ensuring accurate and precise quantification across large sample sets, making them ideal for TMT multiplexing experiments.

FAIMS Pro Duo Interface: Overcome sample complexity

The Thermo Scientific FAIMS Pro Duo Interface enhances selectivity and sensitivity, achieving detection at low picogram and single-cell levels, thus enabling more comprehensive proteome coverage. In TMT multiplexing experiments, FAIMS Pro Duo interface improves quantitative accuracy.

Mass spectrometry solutions for TMT multiplexing

Unleash the Power of Proteomics with the Orbitrap Astral Zoom Mass Spectrometer: Precision, speed and depth for TMT analysis

The Thermo Scientific Orbitrap Astral Zoom Mass Spectrometer provides accurate and reproducible quantitation of thousands of proteins. With its innovative design, the Orbitrap Astral Zoom MS sets a new standard for TMT multiplexing analysis, enabling deeper exploration of the proteome in record time. Combining high speed and sensitivity with high resolution, the Astral analyzer efficiently resolves TMT reporter ions for multiplexed quantitation.

Accuracy, precision and power: Orbitrap Tribrid Apex MultiOmics Mass Spectrometer for TMT analysis

Experience exceptional detection limits and selectivity in full-scan MS mode. The Thermo Scientific Orbitrap Tribrid Apex MultiOmics Mass Spectrometer offers the highest resolving power among our Orbitrap LC-MS instruments. This system features exclusive Real-time Search for Synchronous Precursor Selection MS (SPS MS3), delivering accurate and precise TMT multiplexing quantitation results.

Maximize Efficiency with the Orbitrap Excedion Pro MS for TMT Analysis

The Thermo Scientific Orbitrap Excedion Pro Hybrid Mass Spectrometer enables TMTpro 35plex experiments. When you need ultimate efficiency, the optional Thermo Scientific FAIMS Pro Interface, the next generation ion mobility technology, can be added to boost protein/peptide quantitation efficiency further whilst maintaining the remarkably compact footprint.

Data analysis for TMT multiplexing

Proteome Discoverer Software for experiments that require flexible data analysis

Thermo Scientific Proteome Discoverer Software streamlines TMT multiplexing experiments with predefined workflows, ensuring accurate and precise quantification for multiplexed proteomics studies. With powerful visualization tools and customizable workflows, it simplifies data interpretation, delivering deeper insights into complex TMT datasets.

Our general purpose product lines, including LC-MS products, are not intended for in vitro diagnostic purposes in accordance with our product documentation, manuals, and labels. They are designated for General Laboratory Use Only.

 

Our general purpose product lines have not been tested or validated for such applications and their use for in vitro diagnostic purposes may result in health and safety risks. They are designated for Research Use Only Applications.

 

For Research Use Only - Not For Use In Diagnostic Procedures.

The Thermo Scientific Orbitrap Exploris and Excedion series mass spectrometers are Orbitrap instruments with an atmospheric pressure ionization (API) source for liquid chromatography (LC) mass spectrometry (MS) high-throughput applications. The instruments are designed to be placed on a bench in the laboratory and maintain mass accuracy across chromatographic peaks, supporting confident identification and quantitation using high-resolution accurate-mass detection.