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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ARHGAP 7; Deleted in liver cancer 1 protein; Deleted in liver cancer 1 protein homolog; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC-1; FLJ21120; HP protein; p122 RhoGAP; p122-RhoGAP; rho GTPase activating protein 7; Rho GTPase-activating protein 7; Rho-GTPase-activating protein 7; Rho-type GTPase-activating protein 7; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain-containing protein 12; transfer protein 12
基因别名: A730069N07Rik; ARHGAP7; dlc-1; DLC1; HP; KIAA1723; p122-RhoGAP; RhoGAP; STARD12
UniProt ID: (Human) Q96QB1, (Mouse) Q9R0Z9
Entrez Gene ID: (Human) 10395, (Mouse) 50768, (Rat) 58834
分子生物学功能:
G-protein modulator
protein-binding activity modulator
GTPase-activating protein
