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Proteintech
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Immunogen sequence: IGNYMWDPT TNKSFDIGVN KDSLMPLWWN GSEPLWVTLT KAKRKVYMYY WPGCEVEILG VRPTYCLEYK NVPTDINFAN AVSDALDSFK SGRADLAAIY HERIDVEGHH YGPASPQRKD ALKAVDTVLK YMTKWIQERG LQDRLNVIIF SDHGMTDIFW MDKVIELNKY ISLNDLQQVK DRGPVVSLWP APGKHSEIYN KLSTVEHMTV YEKEAIPSRF YYKKGKFVSP LTLVADEGWF ITENREMLPF WMNSTGRREG WQRGWHGYDN ELMDMRGIFL AFGPDFKSNF RAAPIRSVDV YNVMCNVVGI TPLPNNGSWS RVMCMLKGRA STAPPVWPSH CALALILLFL LA (90-440 aa encoded by BC035035)
Choline-specific glycerophosphodiester phosphodiesterase. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B830047L21Rik; Choline-specific glycerophosphodiester phosphodiesterase; E-NPP 6; E-NPP6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; glycerophosphocholine cholinephosphodiesterase; Glycerophosphocholine cholinephosphodiesterase ENPP6; GPC-Cpde; NPP-6
基因别名: 4833421B01Rik; B830047L21Rik; D8Ertd514e; E-NPP 6; ENPP6; NPP6; UNQ1889/PRO4334
UniProt ID: (Human) Q6UWR7, (Mouse) Q8BGN3
Entrez Gene ID: (Human) 133121, (Mouse) 320981, (Rat) 306460