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Invitrogen
FBXO45 Polyclonal Antibody
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FBXO45 Antibody (PA5-49458) in WB
Western blot analysis of FBXO45 in HT-1080 whole cell lysate. Samples were incubated with FBXO45 polyclonal antibody (Product # PA5-49458) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Predicted band size: 31 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-49458
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 83-115 amino acids from human FBXO45.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons. May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: F-box only protein 45; F-box/SPRY domain-containing protein 1; hFbxo45
基因别名: FBX45; FBXO45
UniProt ID: (Human) P0C2W1
Entrez Gene ID: (Human) 200933
neuron migration
cellular response to DNA damage stimulus
protein ubiquitination
cerebral cortex radially oriented cell migration
cerebral cortex tangential migration
corticospinal tract morphogenesis
anterior commissure morphogenesis
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
synapse assembly involved in innervation
