Immunogen sequence: EDTEYIVHVQ AISIQGQSPA SEPVLFKTPR EAEKMASKNK DEVTMKEMGR NQQLR
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Fibronectin type III domain-containing protein 5, the precursor of irisin, is a protein that is encoded by the FNDC5 gene. This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants.
蛋白别名: Fibronectin type III domain-containing protein 5; Fibronectin type III repeat-containing protein 2; Irisin
基因别名: FNDC5; FRCP2; irisin
UniProt ID: (Human) Q8NAU1
Entrez Gene ID: (Human) 252995