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FZD1 Antibody (PA5-81392) in IHC (P)
Immunohistochemical staining of mouse FZD1 in mouse intestine with FZD1 Polyclonal Antibody (Product # PA5-81392, 1:1,000, formalin-fixed paraffin embedded sections). Left panel: tissue incubated with primary antibody. Right panel: tissue incubated with mixture of primary antibody and antigen (recombinant protein).
产品信息
PA5-81392
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Mouse FZD1 protein (Met1-His248)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2788603
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse FZD1/Frizzled-1.
靶标信息
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chfz-1; Dfrizzled-1; DKFZp564G072; FLJ95923; frizzled; frizzled 1; Frizzled-1; Fz receptor 1; Fz-1; mFz1; Xfrizzled-1
基因别名: AW227548; FZ-1; Fz1; Fzd1
UniProt ID: (Mouse) O70421
Entrez Gene ID: (Mouse) 14362
signal transducer activity
transmembrane signaling receptor activity
G-protein coupled receptor activity
receptor binding
frizzled binding
Wnt-protein binding
PDZ domain binding
identical protein binding
protein homodimerization activity
Wnt-activated receptor activity
protein heterodimerization activity
transmembrane signal receptor
positive regulation of protein phosphorylation
membranous septum morphogenesis
muscular septum morphogenesis
outflow tract morphogenesis
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
cell-cell signaling
multicellular organism development
Wnt signaling pathway
negative regulation of BMP signaling pathway
epithelial cell differentiation
negative regulation of catenin import into nucleus
autocrine signaling
response to drug
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
hard palate development
canonical Wnt signaling pathway
ventricular septum morphogenesis
negative regulation of canonical Wnt signaling pathway
planar cell polarity pathway involved in neural tube closure
