Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-95287
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1 (369-400aa YIAGFLLEDRVVCNDKFAEDGARTVAQG TKKE).
Conjugate
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2807091
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Chfz-1; Dfrizzled-1; DKFZp564G072; FLJ95923; frizzled; frizzled 1; frizzled 1, seven transmembrane spanning receptor; frizzled family receptor 1; frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled-1; Fz receptor 1; Fz-1; FzE1; hFz1; Wnt receptor; Xfrizzled-1
Gene Aliases: FZD1
UniProt ID: (Human) Q9UP38
Entrez Gene ID: (Human) 8321
Molecular Function:
transmembrane signal receptor
positive regulation of protein phosphorylation
membranous septum morphogenesis
muscular septum morphogenesis
outflow tract morphogenesis
G-protein coupled receptor signaling pathway
cell-cell signaling
synapse assembly
neuron differentiation
negative regulation of BMP signaling pathway
epithelial cell differentiation
negative regulation of catenin import into nucleus
autocrine signaling
non-canonical Wnt signaling pathway
response to drug
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
lung alveolus development
positive regulation of sequence-specific DNA binding transcription factor activity
hard palate development
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
cellular response to vitamin D
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
negative regulation of canonical Wnt signaling pathway
planar cell polarity pathway involved in neural tube closure
beta-catenin destruction complex disassembly
Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support