The role of CXC-chemokine receptor CXCR2 and suppressor of cytokine signaling-3 (SOCS-3) in renal cell carcinoma.
Stofas A,Levidou G,Piperi C,Adamopoulos C,Dalagiorgou G,Bamias A,Karadimou A,Lainakis GA,Papadoukakis S,Stravodimos K,Dimopoulos MA,Patsouris E,Gakiopoulou H,Korkolopoulou P
MA5-16010 was used in immunohistochemistry to study the expression and role of CXCR2 and SOCS3 in renal cell carcinoma aggresiveness and metastasis
Tue Mar 04 00:00:00 EST 2014
The role of aberrant VHL/HIF pathway elements in predicting clinical outcome to pazopanib therapy in patients with metastatic clear-cell renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
Choueiri TK,Fay AP,Gagnon R,Lin Y,Bahamon B,Brown V,Rosenberg JE,Hutson TE,Baker-Neblett KL,Carpenter C,Liu Y,Pandite L,Signoretti S
MA5-16010 was used in immunohistochemistry to study the value of analysing VHL/HIF pathway components for predicting the therapeutic response of metastatic clear-cell renal cell carconima patients to pazopanib
Sun Sep 15 00:00:00 EDT 2013
Analysis of biomarker expression in severe endometriosis and determination of possibilities for targeted intraoperative imaging.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
van den Berg LL,Crane LM,van Oosten M,van Dam GM,Simons AH,Hofker HS,Bart J
MA5-16010 was used in immunohistochemistry to study the immunohistochemical expression of a range of biomarkers in order to select a panel suitable for targeted intra-operative imaging of servere endometriosis
Mon Apr 01 00:00:00 EDT 2013
KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer.
Park JJ,Jin YB,Lee YJ,Lee JS,Lee YS,Ko YG,Lee M
MA5-16010 was used in immunohistochemistry to study the mechanism by which the KAI1 metastasis-suppressor gene reduces expression of HIF-1alpha and VEGF in prostate cancer
Tue Mar 06 00:00:00 EST 2012
Immunohistochemical study of the angiogenetic network of VEGF, HIF1α, VEGFR-2 and endothelial nitric oxide synthase (eNOS) in human breast cancer.
Pathology oncology research : POR
Kafousi M,Vrekoussis T,Tsentelierou E,Pavlakis K,Navrozoglou I,Dousias V,Sanidas E,Tsiftsis D,Georgoulias V,Stathopoulos EN
MA5-16010 was used in immunohistochemistry to study the expression of VEGF, VEGFR-2, HIF1-alpha and eNOS in invasive ductal carcinoma
Sun Jan 01 00:00:00 EST 2012
Effects of cigarette smoking on hearing recovery from noise-induced temporary hearing threshold shifts in mice.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Ahn JH,Joo HS,Suh JK,Kim H,So HS,Chung JW
MA5-16010 was used in immunohistochemistry to study the effect of cigarette smoke on noise-induced hearing loss and subsequent recovery in a mouse model
Mon Aug 01 00:00:00 EDT 2011
Astragaloside IV stimulates angiogenesis and increases hypoxia-inducible factor-1α accumulation via phosphatidylinositol 3-kinase/Akt pathway.
The Journal of pharmacology and experimental therapeutics
Zhang L,Liu Q,Lu L,Zhao X,Gao X,Wang Y
MA5-16010 was used in immunohistochemistry to study the mechanism by which astragaloside IV stimulates angiogenesis
Mon Aug 01 00:00:00 EDT 2011
Expression of thioredoxin-1 and hypoxia inducible factor-1α in cerebral arteriovenous malformations: Possible role of redox regulatory factor in neoangiogenic property.
Surgical neurology international
Takagi Y,Kikuta K,Moriwaki T,Aoki T,Nozaki K,Hashimoto N,Miyamoto S
MA5-16010 was used in immunohistochemistry to study the expression and roles of thioredoxin-1 and HIF-1alpha in cerebral arteriovenous malformations
Thu Jul 14 00:00:00 EDT 2011
Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.
Qing G,Skuli N,Mayes PA,Pawel B,Martinez D,Maris JM,Simon MC
MA5-16010 was used in immunohistochemistry to study the role of N-Myc and hypoxia inducible factor HIF-1alpha in the regulation of neuroblastoma tumor progression
Wed Dec 15 00:00:00 EST 2010
Enhancing effects of a chromone glycoside, eucryphin, isolated from Astilbe rhizomes on burn wound repair and its mechanism.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Sumiyoshi M,Kimura Y
MA5-16010 was used in western blot to study the mechanisms underlying the beneficial effects of a chromone glycoside on the repair of burn wounds
Sun Aug 01 00:00:00 EDT 2010
Evaluation of relationship between HIF-1alpha immunoreactivity and stage, grade, angiogenic profile and proliferative index in bladder urothelial carcinomas.
International urology and nephrology
Deniz H,Karakök M,Yagci F,Güldür ME
MA5-16010 was used in immunohistochemistry to study the relationship between HIF-1alpha expression and various prognostic parameters in bladder urothelial carcinomas
Mon Mar 01 00:00:00 EST 2010
Changes in vascular permeability and expression of different angiogenic factors following anti-angiogenic treatment in rat glioma.
Ali MM,Janic B,Babajani-Feremi A,Varma NR,Iskander AS,Anagli J,Arbab AS
MA5-16010 was used in western blot to study changes in vascular parameters, growth factors and tumor size following treatment of rat glioma with a VEGFR tyrosine kinase inhibitor
Fri Jan 15 00:00:00 EST 2010
Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model.
Matsumoto K,Obara N,Ema M,Horie M,Naka A,Takahashi S,Imagawa S
MA5-16010 was used in western blot to study the mechanisms underlying the antitumor effects of 2-oxoglutarate in a murine tumor model
Tue Sep 01 00:00:00 EDT 2009
Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE(-/-) mouse: implications for a "multihit" hypothesis of fatty liver disease.
Free radical biology & medicine
Bailey SM,Mantena SK,Millender-Swain T,Cakir Y,Jhala NC,Chhieng D,Pinkerton KE,Ballinger SW
MA5-16010 was used in immunohistochemistry to study the effects of ethanol and tobacco smoke on hepatic steatosis and hypoxia in hypercholesterolemic apoE(-/-) mice
Wed Apr 01 00:00:00 EDT 2009
Cellular turnover and expression of hypoxic-inducible factor in acute acalculous and calculous cholecystitis.
Critical care (London, England)
Vakkala M,Laurila JJ,Saarnio J,Koivukangas V,Syrjälä H,Karttunen T,Soini Y,Ala-Kokko TI
MA5-16010 was used in immunohistochemistry to study epithelial cell turnover and HIF expression in acute acalculous and calculous cholecystitis
Thu May 29 00:00:00 EDT 2008
Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk.
American journal of physiology. Cell physiology
Agrawal A,Guttapalli A,Narayan S,Albert TJ,Shapiro IM,Risbud MV
MA5-16010 was used in immunocytochemistry to study the role of HIF-1alpha in glycolytic metabolism and the expression of aggrecan in nucleus pulposus cells of the rat intervertebral disc
Wed Aug 01 00:00:00 EDT 2007
Endothelial cell KIT expression in human tumours.
The Journal of pathology
Sihto H,Tynninen O,Bützow R,Saarialho-Kere U,Joensuu H
MA5-16010 was used in immunohistochemistry to study the expression of endothelial cell KIT in a wide of human tumors
Thu Mar 01 00:00:00 EST 2007
Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.
Molecular cancer research : MCR
Pore N,Jiang Z,Shu HK,Bernhard E,Kao GD,Maity A
MA5-16010 was used in western blot to study the mechanism by which Akt1 activation can augment HIF-1alpha expression
Sat Jul 01 00:00:00 EDT 2006
Axial shortening during distraction osteogenesis leads to enhanced bone formation in a rabbit model through the HIF-1alpha/vascular endothelial growth factor system.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Mori S,Akagi M,Kikuyama A,Yasuda Y,Hamanishi C
MA5-16010 was used in immunohistochemistry to study the role of the HIF-1alpha/VEGF system in the enhanced bone formation caused by axial shortening during distraction osteogenesis in a rabbit model
Sat Apr 01 00:00:00 EST 2006
Bimodal effect of hypoxia in cancer: role of hypoxia inducible factor in apoptosis.
Wang Y,Pakunlu RI,Tsao W,Pozharov V,Minko T
MA5-16010 was used in western blot to study the effects of hypoxia and HIF-1alpha antisense oligonucleotides on cancer cells
Mon Jul 11 00:00:00 EDT 2005
Expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in hepatocellular carcinoma: Impact on neovascularization and survival.
World journal of gastroenterology
Huang GW,Yang LY,Lu WQ
MA5-16010 was used in immunohistochemistry to study the expression of hypoxia-inducible factor 1alpha and VEGF in hepatocellular carcinoma
Mon Mar 21 00:00:00 EST 2005
Accumulation of hypoxia-inducible factor-1alpha in mouse inner ear by noise stimulation.
Chung JW,Kang HH,Shin JE,Kim JU
MA5-16010 was used in immunohistochemistry to study the effect of noise stimulation on HIF-1alpha in mouse inner ear
Mon Oct 25 00:00:00 EDT 2004
HIF-VEGF-VEGFR-2, TNF-alpha and IGF pathways are upregulated in critical human skeletal muscle ischemia as studied with DNA array.
Tuomisto TT,Rissanen TT,Vajanto I,Korkeela A,Rutanen J,Ylä-Herttuala S
MA5-16010 was used in immunohistochemistry to study the gene expression patterns in human skeletal muscle obtained from lower limbs amputated due ischemia
Sat May 01 00:00:00 EDT 2004
Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.
Ma W,Tessarollo L,Hong SB,Baba M,Southon E,Back TC,Spence S,Lobe CG,Sharma N,Maher GW,Pack S,Vortmeyer AO,Guo C,Zbar B,Schmidt LS
MA5-16010 was used in immunohistochemistry to study the effects of conditional inactivation of the VHL gene in mice
Mon Sep 01 00:00:00 EDT 2003
Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis.
Cell biology and toxicology
Cangul H,Salnikow K,Yee H,Zagzag D,Commes T,Costa M
MA5-16010 was used in western blot to study the enhanced expression of the novel protein Cap24 in human cancer cells and its potential diagnostic value
Tue Nov 19 00:00:00 EST 2002
Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.
Environmental health perspectives
Cangul H,Salnikow K,Yee H,Zagzag D,Commes T,Costa M
MA5-16010 was used in immunohistochemistry to study the role of HIF-1/hypoxia-related protein Cap43 overexpression in cancer cells
Tue Oct 01 00:00:00 EDT 2002
Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.
The Journal of biological chemistry
Yamashita K,Discher DJ,Hu J,Bishopric NH,Webster KA
MA5-16010 was used in EMSA to study the role of HIF-1, AP-1, GATA-2, and p300/CBP in the regulation of the endothelin-1 gene by hypoxia
Fri Apr 20 00:00:00 EDT 2001
Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes.
Kim MS,Kwon HJ,Lee YM,Baek JH,Jang JE,Lee SW,Moon EJ,Kim HS,Lee SK,Chung HY,Kim CW,Kim KW
MA5-16010 was used in western blot to study the role of histone deacetylases in the regulation of hypoxia-induced angiogenesis
Sun Apr 01 00:00:00 EST 2001