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Proteintech
LOXL2 Polyclonal Antibody
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产品信息
15232-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LOXL2 fusion protein Ag7083
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: AMGLQKKLRL NGGRNPYEGR VEVLVERNGS LVWGMVCGQN WGIVEAMVVC RQLGLGFASN AFQETWYWHG DVNSNKVVMS GVKCSGTELS LAHCRHDGED VACPQGGVQY GAGVACSETA PDLVLNAEMV QQTTYLEDRP MFLLQCAMEE NCLSASAAQT DPTTGYRRLL RFSSQIHNNG QSDFRPKNGR HAWIWHDCHR HYHSMEVFTH YDLLNLNGTK VAEGHKASFC LEDTECEGDI QKNYECANFG DQGITMGCWD MYRHDIDCQW VDITDVPPGD YLFQVVINPN FEVAESDYSN NIMKCRSRYD GHRIWMYNCH IGGSFSEETE KKFEHFSGLL NNQLSPQ
靶标信息
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Lysyl oxidase homolog 2; lysyl oxidase related 2; lysyl oxidase-like 2 delta e13; lysyl oxidase-like 2 protein; Lysyl oxidase-like protein 2; Lysyl oxidase-related protein 2; Lysyl oxidase-related protein WS9-14
基因别名: LOR2; LOXL2; WS9-14
UniProt ID: (Human) Q9Y4K0
Entrez Gene ID: (Human) 4017
response to hypoxia
epithelial to mesenchymal transition
endothelial cell proliferation
sprouting angiogenesis
transcription, DNA-templated
cellular protein modification process
receptor-mediated endocytosis
cell adhesion
aging
histone modification
protein deamination
collagen fibril organization
positive regulation of chondrocyte differentiation
endothelial cell migration
negative regulation of transcription, DNA-templated
response to copper ion
oxidation-reduction process
