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Invitrogen
MTGR1 Polyclonal Antibody
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产品信息
PA5-68898
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of mouse MTGR1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Cow: 86%; Dog: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
靶标信息
Myeloid tumor related gene (MTGR1) is found deleted in acute myeloid leukemia. Overexpression of MTGR1 can stimulate AML1-MTG8 to induce GCSF- dependent proliferation of L-G cells and to interfere with AML1- dependent transcription. AML1/MTG8 functions as a complex with MTGR1 and that the complex might be important in promoting leukemogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CBFA2T2 identified gene homolog; core-binding factor runt domain alpha subunit 2 translocated to 2 homolog; core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog; DKFZp313F2116; MTG8-like protein; MTG8-related protein 1; Protein CBFA2T2; RP5-1137F22.1; ZMYND3 CBFA2T2
基因别名: A430091M07; C330013D05Rik; Cbfa2t2; Cbfa2t2h; MTGR1
UniProt ID: (Mouse) O70374
Entrez Gene ID: (Mouse) 12396
regulation of transcription, DNA-templated
positive regulation of neuron projection development
epithelial cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of nucleic acid-templated transcription
