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Product Details
MA5-21948
产品规格
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2E4
Immunogen
NCKIPSD (NP_909119.1, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
形式
Liquid
浓度
0.2-1.0 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2576870
Product Specific Information
Peptide Sequence: MYRALYAFRS AEPNALAFAA GETFLVLERS SAHWWLAARA RSGETGYVPP AYLRRLQGLE QDVLQAIDRA IEAVHNTAMR DGGKYSLEQR GVLQKLIHH
Target Information
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: 54 kDa VacA-interacting protein; 54 kDa vimentin-interacting protein; 90 kDa SH3 protein interacting with Nck; AF3p21; dia interacting protein; Dia-interacting protein 1; diaphanous protein interacting protein; Diaphanous protein-interacting protein; DIP-1; MGC23891; NCK-interacting protein with SH3 domain; SH3 adapter protein SPIN90; SH3 protein interacting with Nck, 90 kDa; VIP54; WASP-interacting SH3-domain protein; WISH; Wiskott-Aldrich syndrome protein-interacting protein
Gene Aliases: AF3P21; DIP; DIP1; NCKIPSD; ORF1; SPIN90; VIP54; WASLBP; WISH
UniProt ID: (Human) Q9NZQ3
Entrez Gene ID: (Human) 51517
Molecular Function:
scaffold/adaptor protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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