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Abnova
NEK2 Polyclonal Antibody, MaxPab™
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NEK2 Antibody (H00004751-D01P) in WB
Western Blot analysis of NEK2 expression in transfected 293T cell line (H00004751-T02) by NEK2 MaxPab polyclonal antibody.
Lane 1: NEK2 transfected lysate(51.80 KDa).
Lane 2: Non-transfected lysate.
Lane 1: NEK2 transfected lysate(51.80 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00004751-D01P
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NEK2 (NP_002488.1, 1 a.a. approximately 445 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MPSRAEDYEV LYTIGTGSYG RCQKIRRKSD GKILVWKELD YGSMTEAEKQ MLVSEVNLLR ELKHPNIVRY YDRIIDRTNT TLYIVMEYCE GGDLASVITK GTKERQYLDE EFVLRVMTQL TLALKECHRR SDGGHTVLHR DLKPANVFLD GKQNVKLGDF GLARILNHDT SFAKTFVGTP YYMSPEQMNR MSYNEKSDIW SLGCLLYELC ALMPPFTAFS QKELAGKIRE GKFRRIPYRY SDELNEIITR MLNLKDYHRP SVEEILENPL IADLVADEQR RNLERRGRQL GEPEKSQDSS PVLSELKLKE IQLQERERAL KAREERLEQK EQELCVRERL AEDKLARAEN LLKNYSLLKE RKFLSLASNP ELLNLPSSVI KKKVHFSGES KENIMRSENS ESQLTSKSKC KDLKKRLHAA QLRAQALSDI EKNYQLKSRQ ILGMR
靶标信息
NEK2 is involved in cell cycle regulation and is essential for faithful chromosome segregation. NEK2 is a gene that encodes for a serine/threonine-protein kinase. This protein plays a crucial role in the regulation of mitosis and is primarily located in the centrosome. During the G1 phase, the protein is undetectable, but its levels progressively increase throughout the S phase, reaching their peak in late G2 phase. The gene has several alternatively spliced transcript variants that encode different isoforms with distinct C-termini. NEK2 is associated with several diseases, including Retinitis Pigmentosa 67 and Retinitis Pigmentosa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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