应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:1,000-1:10,000 | - |
免疫组化(石蜡) (IHC (P)) |
1:100 | - |
免疫组化(冰冻) (IHC (F)) |
1:100 | - |
免疫细胞化学 (ICC/IF) |
1:50 | - |
流式细胞分析 (Flow) |
Assay-Dependent | - |
产品规格 | |
---|---|
种属反应 |
Dog, Human, Mouse, Non-human primate, Rat |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
A180 |
抗原 |
Full length recombinant NQO1 (from human lung). |
偶联物 |
DyLight™ 550
|
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein G |
保存液 |
50mM sodium borate |
内含物 |
no preservative |
保存条件 |
4° C, store in dark |
RRID |
AB_11152120 |
This antibody does not react with mouse samples.
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Altered expression of the protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: Azoreductase; Diaphorase (NADH/NADPH); diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase 4; diaphorase 4 (NADH/NADPH); diaphorase-4; dioxin-inducible 1; DT-diaphorase; DTD; Menadione reductase; NAD(P)H dehydrogenase (quinone); NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H menadione oxidoreductase 1, dioxin inducible; NAD(P)H:menadione oxidoreductase; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NQ01; Phylloquinone reductase; QR1; Quinone reductase 1
基因别名: AV001255; DHQU; DIA4; DTD; Nmo-1; Nmo1; NMOR1; NMORI; NQO1; Ox-1; Ox1; QR1
UniProt ID: (Human) P15559, (Mouse) Q64669, (Rat) P05982
Entrez Gene ID: (Dog) 610935, (Human) 1728, (Mouse) 18104, (Rat) 24314
分子生物学功能:
oxidoreductase