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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Proteasomal ATPase-associated factor 1; Protein G-16; WD repeat-containing protein 71
基因别名: PAAF1; WDR71
Entrez Gene ID: (Human) 80227