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Proteintech
PAOX Polyclonal Antibody
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产品信息
18972-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PAOX Fusion Protein Ag5777 (31-364 aa encoded by BC032778)
偶联物
形式
Liquid
浓度
0.16 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RLCGHSAFP HLRVLEATAR AGGRIRSERC FGGVVEVGAH WIHGPSRGNP VFQLAAEYGL LGEKELSQEN QLVETGGHVG LPSVSYASSG ASVSLQLVAE MATLFYGLID QTREFLHAAE TPVPSVGEYL KKEIGQHVAG WTEDEETRKL KLAVLNSFFN LECCVSGTHS MDLVALAPFG EYTVLPGLDC TFSKGYQGLT NCMMAALPED TVVFEKPVKT IHWNGSFQEA AFPGETFPVS VECEDGDRFP AHHVIVTVPL GFLREHLDTF FDPPLPAEKA EAIRKIGFGT NNKIFLEFEE PFWEPDCQLI QLVWEDTSPL EDAAPELQDA WFRKL (31-364 aa encoded by B C032778)
靶标信息
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: exo-N4-amino; Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase; Polyamine oxidase; putative GTP-binding protein
基因别名: 2410012F02Rik; AI118225; PAO; PAOX; UNQ1923/PRO4398
UniProt ID: (Human) Q6QHF9, (Mouse) Q8C0L6
Entrez Gene ID: (Human) 196743, (Mouse) 212503, (Rat) 293589
receptor binding
polyamine oxidase activity
N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
spermine:oxygen oxidoreductase (spermidine-forming) activity
spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity
N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
oxidoreductase activity
oxidase
