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Invitrogen
PDGFRA Monoclonal Antibody (16A1), APC
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产品信息
A15718
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
16A1
抗原
CD140a-transfected NIH 3T3 cells
偶联物
激发/发射光谱
651/660 nm
查看光谱
形式
Liquid
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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