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Invitrogen
PNLDC1 Recombinant Rabbit Monoclonal Antibody (PSH09-60)
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PNLDC1 Antibody (MA570091) in WB
Western blot analysis of PNLDC1 in various lysates. Samples were incubated with PNLDC1 monoclonal antibody (Product # MA570091) using a dilution of 1:2,000 in 5% NFDM/TBST at 4°C overnight followed by Goat Anti-Rabbit IgG - HRP Secondary Antibody at a dilution of 1:50,000 for 1 hour at room temperature. Lane 1: 293T cell lysate; Lane 2: LNCaP cell lysate; Lane 3: Raji cell lysate; Lane 4: Mouse testis tissue lysate; Lane 5: Rat testis tissue lysate. Lysates/proteins at 20 µg/Lane. Predicted band size: 60 kDa; Observed band size: 60 kDa. Ex... View More
产品信息
MA570091
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH09-60
抗原
Recombinant protein within human PNLDC1 aa 101-250.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: 293T cell lysate, LNCaP cell lysate, Raji cell lysate, Mouse testis tissue lysate, Rat testis tissue lysate.
Subcellular location: Endoplasmic reticulum membrane.
靶标信息
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HsPNLDC1; PARN-like domain-containing protein 1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease domain-containing protein 1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1; Poly(A)-specific ribonuclease PNLDC1
基因别名: Gm313; PNLDC1
UniProt ID: (Human) Q8NA58, (Mouse) B2RXZ1
Entrez Gene ID: (Human) 154197, (Rat) 361478, (Mouse) 240023
