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Antibodies Inc
Pan-MAGUK Monoclonal Antibody (K28/86)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-029
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat,
Xenopus,
Zebrafish
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
K28/86
抗原
Fusion protein amino acids 77-299 of human PSD-95/SAP90 produced recombinantly in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
Pan-MAGUK refers to the collective group of Membrane-Associated Guanylate Kinase (MAGUK) family proteins, which are scaffolding proteins involved in organizing signaling complexes at cellular membranes. These proteins play critical roles in synaptic signaling, cell adhesion, and maintaining the structure of tight junctions. Dysregulation of MAGUK proteins has been linked to various neurological disorders and cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Channel-associated protein of synapse-110; Chapsyn-110; discs large homolog 2; discs large homolog 3; discs large homolog 4; discs, large homolog 4; Disks large homolog 1; Disks large homolog 2; Disks large homolog 3; Disks large homolog 4; Drosophila discs-large tumor suppressor homologue (synapse associated protein); E-dlg/SAP97; Embryo-dlg/synapse-associated protein 97; hDlg; membrane associated guanylate kinase; MAGUK; Neuroendocrine-DLG; Postsynaptic density protein 93; Postsynaptic density protein 95; Postsynaptic density protein PSD-93; PSD-93; PSD-95; PSD-95 alpha 2b; PSD-95 beta; PSD-95/SAP90-related protein 1; SAP-102; SAP-90; SAP-97; SAP-97A; SAP102; SAP97A; Synapse-associated protein 102; Synapse-associated protein 90; Synapse-associated protein 97; Synapse-associated protein 97A; synapse-associated protein SAP90; synaptic density protein PSD-93; XLMR
基因别名: A330103J02Rik; B130052P05Rik; B230218P12Rik; B330007M19Rik; DLG1; DLG2; DLG3; DLG4; Dlgh1; Dlgh2; Dlgh3; Dlgh4; E-dlg/SAP97; fa66c08; fa66e02; fd02c12; fu95c12; Gm1197; im:7138640; KIAA1232; mKIAA1232; mKIAA4187; PSD-93; PSD-95; PSD93; PSD95; sap-90; SAP-97; SAP-97A; SAP102; SAP90; SAP90A; SAP97; si:ch211-276g21.1; wu:fa66c08; wu:fa66e02; wu:fc34d02; wu:fd02c12; wu:fu95c12; zgc:55810
guanylate kinase activity
protein binding
protein C-terminus binding
potassium channel regulator activity
protein kinase binding
phosphatase binding
PDZ domain binding
mitogen-activated protein kinase kinase binding
protein complex scaffold
ionotropic glutamate receptor binding
ion channel binding
L27 domain binding
kinase binding
protein phosphatase binding
protein heterodimerization activity
protein domain specific binding
ubiquitin protein ligase binding
receptor binding
beta-1 adrenergic receptor binding
D1 dopamine receptor binding
P2Y1 nucleotide receptor binding
protein complex binding
acetylcholine receptor binding
glutamate receptor binding
scaffold protein binding
structural molecule activity
neurexin family protein binding
neuroligin family protein binding
scaffold/adaptor protein
ureteric bud development
branching involved in ureteric bud morphogenesis
immunological synapse formation
endothelial cell proliferation
lens development in camera-type eye
T cell cytokine production
actin filament organization
cell adhesion
chemical synaptic transmission
nervous system development
protein localization
positive regulation of cell proliferation
single organismal cell-cell adhesion
peristalsis
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
membrane raft organization
regulation of myelination
activation of protein kinase activity
regulation of protein localization
T cell activation
negative regulation of T cell proliferation
regulation of membrane potential
amyloid precursor protein metabolic process
receptor clustering
positive regulation of potassium ion transport
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
nucleotide phosphorylation
reproductive structure development
embryonic skeletal system morphogenesis
tissue morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
negative regulation of protein kinase B signaling
hard palate development
bicellular tight junction assembly
protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
receptor localization to synapse
positive regulation of multicellular organism growth
positive regulation of developmental growth
negative regulation of phosphatase activity
sensory perception of pain
neuronal ion channel clustering
establishment of planar polarity
negative regulation of receptor internalization
protein complex assembly
positive regulation of cytosolic calcium ion concentration
synaptic vesicle maturation
social behavior
protein localization to synapse
locomotory exploration behavior
establishment of protein localization
regulation of long-term neuronal synaptic plasticity
positive regulation of synaptic transmission
neuromuscular process controlling balance
dendritic spine morphogenesis
vocalization behavior
AMPA glutamate receptor clustering
regulation of N-methyl-D-aspartate selective glutamate receptor activity
positive regulation of excitatory postsynaptic potential
regulation of grooming behavior
signal transduction
locomotory behavior
response to cocaine
regulation of neuronal synaptic plasticity
embryo development
cell-cell adhesion
neurotransmitter receptor localization to postsynaptic specialization membrane
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