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Invitrogen
Phospho-HPRT1 (Ser110) Polyclonal Antibody
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Phospho-HPRT1 (Ser110) Antibody (PA5-105342) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-HPRT1 (Ser110) in human kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-HPRT1 (Ser110) polyclonal antibody (Product # PA5-105342) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105342
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HPRT1(Accession P00492), corresponding to amino acid residues around phosphorylated Ser110.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of HPRT1 only when phosphorylated at Ser110.
靶标信息
The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGPRT; HGPRTase; HPRT 1; HPRT B; hypoxanthine guanine phosphoribosyl transferase 1; hypoxanthine phosphoribosyl transferase; Hypoxanthine-guanine phosphoribosyltransferase
基因别名: C81579; Hgprtase; HPGRT; HPRT; HPRT1
UniProt ID: (Mouse) P00493, (Rat) P27605
Entrez Gene ID: (Mouse) 15452, (Rat) 24465
nucleotide binding
magnesium ion binding
hypoxanthine phosphoribosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
identical protein binding
protein homodimerization activity
metal ion binding
guanine phosphoribosyltransferase activity
glycosyltransferase
response to amphetamine
purine nucleotide biosynthetic process
purine ribonucleoside salvage
adenine salvage
guanine salvage
grooming behavior
locomotory behavior
nucleoside metabolic process
cytolysis
striatum development
cerebral cortex neuron differentiation
central nervous system neuron development
GMP salvage
IMP salvage
dopamine metabolic process
hypoxanthine salvage
positive regulation of dopamine metabolic process
GMP catabolic process
IMP metabolic process
adenine metabolic process
hypoxanthine metabolic process
lymphocyte proliferation
dendrite morphogenesis
protein homotetramerization
spermatogenesis
brain development
cellular response to insulin stimulus
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