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Invitrogen
RFC5 Polyclonal Antibody
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产品信息
PA1-26571
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a portion of human Replication Factor C 5 36 kDa subunit encoded within exon 1.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-26571 detects RFC5 from human samples. PA1-26571 will not react with mouse or rat.
PA1-26571 has been successfully used in Western blot procedures where a band of 36 kDa is predicted to be detected. HeLa cell nucleaer extract is recommended as a positive control fo PA1-26571.
The PA1-26571 immunogen is a synthetic peptide corresponding to a portion of human Replication Factor C 5 36 kDa subunit encoded within exon 1.
靶标信息
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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