FIGURE: 1 / 2
Peptide Sequence: DIIGPLDAKG LLFSASKQDL LRTKMRECEL LLQECAHQTT KLGRKVETIT IIYDCEGLGL KHLWKPAVEA YGEFLCMFEE NYPETLKRLF VVKAPKLFP
This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Protein Aliases: Alpha-tocopherol-associated protein; SEC14-like lipid binding 2; SEC14-like protein 2; SPF; Squalene transfer protein; Supernatant protein factor; TAP; tocopherol-associated protein; tocopherol-associated protein 1
Gene Aliases: C22orf6; KIAA1186; KIAA1658; SEC14L2; SPF; TAP; TAP1
UniProt ID: (Human) O76054
Entrez Gene ID: (Human) 23541