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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: ESSDLLYTPS YSLPFSYHYG HFPLDSHVFS SKKPMLPAKF GQPQGSPCEV ARFFLSTLPA SGECQWHYAN PLVPSSSSPA KNPPEPPANT ARHSLVPSYE
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHe15; Class E basic helix-loop-helix protein 15; Single-minded homolog 2
基因别名: BHLHE15; SIM2
Entrez Gene ID: (Human) 6493