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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
2 µg/mL | - |
免疫细胞化学 (ICC/IF) |
1:500 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide between amino acids 300-355 of the human SIRT6 protein. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.05 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
tris citrate, pH 7-8 |
内含物 |
0.1% sodium azide |
保存条件 |
4° C, do not freeze |
RRID |
AB_2188919 |
PA1-16957 is specific for the ~39 kDa SIRT6 protein.
A higher molecular weight band at ~59 kDa may be seen with lower dilutions such as 2 µg/mL.
Suggested positive control: antigen standard for SIRT6 (transient overexpression lysate), Hela whole cell extract.
Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; SIR2-like protein 6; sir2-related protein type 6; sirtuin type 6
基因别名: SIR2L6; SIRT6
UniProt ID: (Human) Q8N6T7
Entrez Gene ID: (Human) 51548
