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PA1-16958 is specific for the ~37 kDa SIRT6 protein.
A non-specific higher molecular weight band can be seen at ~61 kDa of equal or greater intensity than the mSIRT6 band.
Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.
仅用于科研。不用于诊断过程。未经明确授权不得转售。