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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TTDAARRIYD ETQGRQQVLP LDSIYKKTLP DWKRSLPHFR NGKLYFKPIG DPVFARDLLT FPDNVEHCET VFGMLLGDTI ILDNLDAANH YRKEVVKITH CPTLLTRDGD RIRSNGKFGG LQNKAPPMDK LRGMVFGAPV PKQCLILGEQ IDLLQQYRSA VCKLDSVNKD LNSQLEYLRT PDMRKKKQEL DEHEKNLKLI EEKLGMTPIR KCNDSLRHSP KVETTDCPVP PKRMRREATR QNRIITKTDV; Positive Samples: HL-60, SKOV3, Jurkat, U-251MG, HepG2, Rat brain; Cellular Location: Chromosome
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: structural maintenance of chromosomes flexible hinge domain containing 1
基因别名: RGD1307234
Entrez Gene ID: (Rat) 316732