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Proteintech
SPZ1 Polyclonal Antibody
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产品信息
18931-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SPZ1 Fusion Protein Ag6995 (1-430 aa encoded by BC033798)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MASSAKSAE MPTISKTLNP TPDPHQEYLD PRITIALFEI GSHSPSSWGS LPFLKNSSHQ VTEQQTAQKF NNLLKEIKDI LKNMAGFEEK ITEAKELFEE TNITEDVSAH KENIRGLDKI NEMLSTNLPV SLAPEKEDNE KKQEMILETN ITEDVSAHKE NIRGLDKINE MLSTNLPVSL APEKEDNEKK QQMIMENQNS ENTAQVFARD LVNRLEEKKV LNETQQSQEK AKNRLNVQEE TMKIRNNMEQ LLQEAEHWSK QHTELSKLIK SYQKSQKDIS ETLGNNGVGF QTQPNNEVSA KHELEEQVKK LSHDTYSLQL MAALLENECQ ILQQRVEILK ELHHQKQGTL QEKPIQINYK QDKKNQKPSE AKKVEMYKQN KQAMKGTFWK KDRSCRSLDV CLNKKACNTQ FNIHVARKAL RGKMRSASSL R (1-430 aa encoded by BC033798)
靶标信息
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: protein phosphatase 1, regulatory subunit 148; Spermatogenic leucine zipper protein 1; spermatogenic zip 1; testis secretory sperm-binding protein Li 232m; Testis-specific protein 1; Testis-specific protein NYD-TSP1
基因别名: NYD-TSP1; PPP1R148; SPZ1; TSP1
UniProt ID: (Human) Q9BXG8
Entrez Gene ID: (Human) 84654
