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Immunogen sequence: GKENNKLEVLK KTCKKKKMAG GARKLVQPIA LDPSGRPVFP IGLGGLTVYS L
Highest antigen sequence identity to the following orthologs - mouse 90%, rat 88%.
TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Nuclear interactor of ARF and Mdm2; Transforming growth factor beta regulator 1
基因别名: NIAM; TB-5; TBRG1
UniProt ID: (Human) Q3YBR2
Entrez Gene ID: (Human) 84897