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Recommended positive controls: 293T.
Predicted reactivity: Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHe34; Class E basic helix-loop-helix protein 34; hTFEC-L; TFE-C; Transcription factor EC; Transcription factor EC-like
基因别名: BHLHE34; hTFEC-L; TCFEC; TFE-C; TFEC; TFEC-L; TFECL
UniProt ID: (Human) O14948
Entrez Gene ID: (Human) 22797