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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total USP9X.
USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity. USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Deubiquitinating enzyme FAF-X; Fat facets homolog; Fat facets in mammals; Fat facets protein-related, X-linked; fats facets protein related, X; hFAM; probable ubiquitin carboxyl-terminal hydrolase FAF-X; Ubiquitin carboxyl-terminal hydrolase 9X; Ubiquitin carboxyl-terminal hydrolase FAM; ubiquitin specific peptidase 9, X chromosome; ubiquitin specific protease 9 SSSRF- isoform; ubiquitin specific protease 9, X chromosome; Ubiquitin thioesterase FAF-X; ubiquitin thiolesterase FAF-X; Ubiquitin-specific protease 9, X chromosome; Ubiquitin-specific-processing protease FAF-X
基因别名: 5730589N07Rik; AA407302; AA407699; AL022658; AL022749; DFFRX; FAF-X; Fafl; FAM; RGD1560056; USP9; USP9X
UniProt ID: (Mouse) P70398
Entrez Gene ID: (Mouse) 22284, (Rat) 363445