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产品信息
H00008239-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C4
抗原
USP9X (NP_068706, 1 a.a. approximately 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MTATTRGSPV GGNDNQGQAP DGQSQPPLQQ NQTSSPDSSN ENSPATPPDE QGQGDAPPQL EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP
靶标信息
USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity. USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme FAF-X; Drosophila fat facets related, X-linked; Fat facets in mammals; fat facets protein related, X-linked; Fat facets protein-related, X-linked; hFAM; Ubiquitin carboxyl-terminal hydrolase 9X; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila); Ubiquitin thioesterase FAF-X; ubiquitin thiolesterase FAF-X; ubiquitin-specific processing protease FAF-X; Ubiquitin-specific protease 9, X chromosome; Ubiquitin-specific-processing protease FAF-X
基因别名: DFFRX; FAF; FAM; MRX99; MRXS99F; USP9; USP9X
UniProt ID: (Human) Q93008
Entrez Gene ID: (Human) 8239
negative regulation of transcription from RNA polymerase II promoter
neuron migration
ubiquitin-dependent protein catabolic process
chromosome segregation
mitotic nuclear division
transforming growth factor beta receptor signaling pathway
female gamete generation
protein deubiquitination
BMP signaling pathway
cellular protein metabolic process
axon extension
cell division
