Our latest research findings in drug discovery and ADME/Tox are illustrated through posters presented at conferences like SBS, AACR and others; and through peer-reviewed articles. View some of our most recent publications in the table below.

TitleAuthorsReference
A Fluorescence Polarization Assay for the Muscarinic M1 G-protein Coupled Receptor  KG Huwiler, T De Rosier, BJ Hanson, KW Vogel.Assay Drug Dev Technol. 2010 Jun;8(3):356-66.
Multi-Pathway Cellular Analysis of Compound SelectivityMichael K. Hancock, Connie S. Lebakken, Jun Wang, Kun BiMol Biosyst. 2010 Oct 1;6(10):1834-43.
ADP Detection TechnologiesLowery RG, Vogel K, Till J.Assay Drug Dev Technol. 2010 Aug;8(4):1-2
Development and Validation of a Cell-Based Assay for the Nuclear Receptor Retinoid-Related Orphan Receptor GammaWilkinson J, Hallis T, Hermanson S, Bi KAssay Drug Dev Technol. 2010 Nov 4. [Epub ahead of print]
Commentary: Prioritizing hits based on drug-target residence timeVogel KWDrug Discovery News, Sept 2010, p13
Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors.De SK, Chen V, Stebbins JL, Chen LH, Cellitti JF, Machleidt T, Barile E, Riel-Mehan M, Dahl R, Yang L, Emdadi A, Murphy R, Pellecchia M.Bioorg Med Chem. 2010 Jan 15;18(2):590-6.
Covalent peroxisome proliferator-activated receptor{gamma} binding by nitro-fatty acids: Endogenous ligands act as selective modulators.Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, Xu HE, Batthyany CI, Chen YE, Hallis TM, Freeman BA.J Biol Chem. 2010 Apr 16;285(16):12321-33.
Multiplexing terbium- and europium-based TR-FRET readouts to increase kinase assay capacity.Vogel KW, Horton RJ Biomol Screen. 2010 Sep;15(8):1008-15.
Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation.Davis AA, Heilman CJ, Brady AE, Miller NR, Fuerstenau-Sharp M, Hanson BJ, Lindsley CW, Conn PJ, Lah JJ, Levey AI.ACS Chem Neurosci. 2010 Aug 18;1(8):542-551.
Development of a GPR23 cell-based β-lactamase reporter assay.Lee PH, Hanson BJ.Methods Enzymol. 2010;485:349-68
Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.
Robers MB, Loh C, Carlson CB, Yang H, Frey EA, Hermanson SB, Bi K.Mol Biosyst. 2011 Jan 1;7(1):59-66.

仅供科研使用，不可用于诊断目的。

CMD SchemaApp code