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Invitrogen
Canine SCF/KITLG ELISA Kit
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产品规格
检测灵敏度
0.065 ng/mL
测定范围
0.065-16 ng/mL
检测样本类型/体积
{Serum=50 µL, Plasma=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
SCF
均相（无需洗涤）
Dog
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Canine SCF/KITLG quantitates canine SCF/KITLG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine SCF/KITLG.
靶标信息
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : 710-712, CSF, KITLG, MGF
基因ID : (Dog) 403507
基因符号 : KITLG
蛋白别名 : c-Kit ligand, DKFZp686F2250, H-SCF, kit-ligand, M-SCF, Kit ligand, Mast cell growth factor, MGF, SCF, Stem cell factor, stem cell factor, CSF
UniProt ID (Dog) Q06220
