Creatinine ELISA Kits

靶标信息

Creatinine is a nitrogenous waste molecule generated from muscle metabolism and is predominantly filtered through the kidneys to be excreted in urine. Although not directly encoded by a gene itself, its levels are significant for assessing kidney function, with serum creatinine being a key biomarker in nephrology. Creatinine evaluation serves as a primary tool for estimating the glomerular filtration rate (eGFR), offering an indirect measure of renal performance. Despite its prevalence in medical diagnostics, creatinine measurement has notable limitations due to its susceptibility to variations influenced by factors such as muscle mass, diet, age, and ethnicity, making it less reliable under certain conditions. Advanced methods now incorporate cystatin C alongside creatinine to enhance equation accuracy for eGFR estimations and mitigate racial biases in clinical settings. The metabolism of creatinine and its physiological significance underscores its utility as a cost-effective, accessible measure for kidney function, despite its shortcomings.